Progesterone and PMS

In my own experiment, a nightly dose of 12-18mg of progesterone (as Progest-E) administered during days 14-28 of the of menstrual cycle (beginning with ovulation and ending with the first day of menstruation) alleviated most of the symptoms of PMS and eliminated the need for painkillers in a subject who regularly took ibuprofen to mitigate the pain from menstrual cramps.


Progesterone, by blocking estrogen’s blockage of the thyroid hormone, should promote the effect of thyroxin and raise the temperature. The metabolism is shifted toward oxidation of fat, with the result that sugar is spared for the brain and kidneys and, in pregnancy, for the fetus.